KMID : 0359719950130020390
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Journal of the Korean Neurological Association 1995 Volume.13 No. 2 p.390 ~ p.395
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A Case of Stiff-Man Syndrome Associated with Panhypopituitarism
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Abstract
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Stiff-man syndrome is a rare disorder characterized by intermittent spasms and stiffness of the axial and limb muscles, associated with an electromyographic pattern of continuous motor unit activity in affected muscles. The cause of this disorder
is
unknown, but it has been associated with autoimmune disease and with endocrine disorder. We present a 49 year old female patient with clinical and electrophysiologic features of stiff-man syndrome and postoperative panhypopituitarism, whose
muscle
stiffness and spasm resolved with diazepam, clonazepam and prednisolonereplacement therapy.
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KEYWORD
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